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ACUTE LEUKEMIA (ACUTE MYELOID LEUKEMIA)

GENERAL

Clinical Manifestations	Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. In AML, the bone marrow makes abnormal myeloblasts (a type of white blood cell). These abnormal cells are called leukemia cells, or blasts. Acute leukemia is monitored by measuring the amount of blasts. Because it is a rapidly progressing cancer, the cells divide quickly and the disease may spread fast. As the percentage of blasts increases, the bone marrow is less able to create normal white and red blood cells and platelets.
Treatment Principle
Herb Formulas	Decoct and drink 15g Hb. Catharanthi Chang Chu Hua. Decoct 30g Hb Senecionis Scandens Qian Li Guang and 60g Hb. Galii Aparinis Zhu Yang Yang For skin abscess associated with acute granular leukemia: For skin abscess associated with acute granular leukemia: Skin Abscess Topical #1
Points

WIND-COLD WITH INTERIOR HEAT

Clinical Manifestations	Fever and chills Maybe fever only Skin eruptions Achiness Anhidrosis Headache Cough Asthma Aversion to cold Edema Thirst Restlessness Irritability Fidgeting Constipation Sometimes dry achy eyes T: Normal or red C: Yellow or white P: Floating and tight or rapid
Treatment Principle	Expel Wind Disperse Cold Cool Heat
Herb Formulas	Da Qing Long Tang
Points	DU-14, DU-16, GB-20, LI-4, LI-11, LU-7, LU-9, LU-10, SJ-5, SP-1, SP-2, ST-44, UB-12, UB-13

WIND-HEAT ATTACKS THE LUNGS WITH UNDERLYING SPLEEN AND STOMACH HEAT

Clinical Manifestations	Severe sore and swollen throat High fever with convulsions in infants Difficulty swallowing Carbuncles Acute localized infection Lymphangitis Furuncles Boils Abscesses T: Red C: Greasy and yellow P: Rapid
Treatment Principle	Relieve Toxic Heat Reduce swelling Alleviate pain
Herb Formulas	Liu Shen Wan (can be used as a gargle)
Points	DU-14, DU-16, GB-20, LI-4 + LU-7 or LI-4 + SJ-5, LU-5, LU-10, LU-11, ST-44, UB-12, UB-13

QI AND XUE STAGE FIRE

Clinical Manifestations	Intense fever Strong thirst Dry heaves Severe, stabbing headache Extreme irritability Delirious speech (severe) Rash (severe) Epistaxis (severe) Maculae Mania Convulsions Lips chapped, dark and scorched Coma Hematemesis Extreme coldness of the extremities Restlessness Spasms or convulsions Blurred vision T: Dark red C: Dry or prickly P: Deep, thin and rapid or Floating, large and rapid
Treatment Principle	Clear Heat Relieve toxicity Cool the Blood Drain Fire Stop bleeding
Herb Formulas	Qing Wen Bai Du Yin
Points

YING STAGE HEAT (YING RE)

Clinical Manifestations	High fever, worse at night Insomnia Irritability Mild thirst with no desire to drink Mental disturbance Speech disturbance Red, dry, painful rashes T: Deep red C: Little or None P: Thready and rapid
Treatment Principle	Reduce Heat in the Ying Detoxify
Herb Formulas	Qing Ying Tang
Points	HT-3, HT-5, HT-6, HT-7, KI-3, LI-11, PC-7, PC-8, bleed Shixuan, Sifeng, SP-6

STOMACH AND LIVER FIRE

Clinical Manifestations	Headache Dizziness Red eyes Tinnitus Oral ulcers Bleeding gums Constipation T: Red C: Yellow P: Wiry and Rapid
Treatment Principle	Purge Fire Detoxify
Herb Formulas	Huang Lian Jie Du Tang
Points

LIVER FIRE

Clinical Manifestations	Hypochondriac pain Headache Dizziness Red sore eyes Hearing loss Swelling in the ears Bitter taste in the mouth Irritability Short temper Difficult and painful urination with a heat sensation in the urethra Swollen and itchy genitalia Yellow, foul smelling leukorrhea Short menstrual cycle with reddish-purple blood Ear discharge Yellow urine Chest pain Constipation Turbid urine Dry throat Hematuria Pain in the armpits Sweating in the groin T: Red or Red edges C: Yellow or Yellow and greasy P: Wiry, Excess and rapid
Treatment Principle	Drain Excess Fire from the Liver and Gallbladder
Herb Formulas	Long Dan Xie Gan Tang
Points

QI AND YIN DEFICIENCY WITH EMPTY FIRE

Clinical Manifestations	Acute mononuclear leukemia Fatigue Spontaneous sweating A pale face Poor appetite Loose stools Dizziness Weak voice/reluctance to speak Five Sole Heat Malar flush Night sweats Anxiety Hot flashes T: Pale, Pale red or Red C: Thin white, Little or None P: Deep and weak or Thready and rapid
Treatment Principle	Tonify Qi Nourish Yin Nourish the Blood Restrain Yang Astringe sweat Inhibit the growth of cancer cells
Herb Formulas	Acute Leukemia #3
Points

BLOOD HEAT

Clinical Manifestations	Chronic, stubborn skin lesions Sores Enlarged lymph nodes Nodules Red itching skin Hardness T: Pale with red spots P: Rapid and pecking
Treatment Principle	Clear Heat Cool the Blood Dissipate swellings Dispel noxious sores Disperse nodules and hardness
Herb Formulas	Ji Zheng Xue Ai Tang Er Hao
Points

TOXIC HEAT

Clinical Manifestations	High fever Thirst Epistaxis Constipation Scanty, red urine Hemorrhaging Loss of consciousness Weakness Bleeds easily T: Red C: Yellow P: Tight or Thready and rapid
Treatment Principle	Disperse Heat Relieve toxicity
Herb Formulas	Acute Leukemia #5 With Blood Deficiency: Acute Leukemia #6
Points

TOXIC HEAT WITH RESIDUAL EXTERIOR SYMPTOMS

Clinical Manifestations	Acute high fever Chills Flushed face Dry nose and mouth Extreme thirst Listlessness Insomnia Dryness of the teeth Irritability Oliguria with reddish urine Anhidrosis Severe headache Delirium Skin eruptions Epistaxis Hemorrhage T: Red and dry C: Yellow P: Large and rapid or Smooth and rapid or Wiry and rapid
Treatment Principle	Cool Heat Relieve inflammation
Herb Formulas	San Huang Shi Gao Tang
Points

TOXIC HEAT WITH BLOOD STAGNATION AND PHLEGM

Clinical Manifestations	Stabbing pain in the epigastrium which is worse with pressure Substantial or insubstantial mass beneath the Heart which is painful on palpation Vomiting food mixed with Blood Dry, black stools Melaena Dry skin Local redness Swelling and pain Maybe fever and chills T: Normal or Purple or Purple spots C: Thin white or yellow P: Rapid and forceful or Deep and thready or Choppy
Treatment Principle	Invigorate the Blood Break up Stasis Clear Heat Resolve toxicity Resolve Phlegm
Herb Formulas	Yan Zhong Wan Yi Hao
Points

TOXIC HEAT WITH YIN DEFICIENCY FIRE

Clinical Manifestations	Long-standing illness Pain Redness Fatigue Fever Anxiety Dry mouth Thirst Dark urine Bitter taste Red eyes Insomnia Burning pain in the Stomach Chest and hypochondriac pain A sensation of Heat in the chest Five sole Heat Constipation Dry mouth and throat Episodic hematuria with fresh red Blood The urine may be concentrated T: Red C: Little or None or White or Yellow and greasy or Thick, sticky, dry and yellow P: Thready and rapid or Wiry or Rolling and rapid or Wiry, overflowing and rapid
Treatment Principle	Clear Heat Resolve toxicity Cool and invigorate the Blood Clear Damp-Heat Drain Yin Deficiency Fire Nourish Qi and Yin
Herb Formulas	Acute Leukemia #1 Xi Jiao Di Huang Tang Acute Leukemia #4
Points

TOXIC HEAT WITH QI AND BLOOD DEFICIENCY

Clinical Manifestations	Long-standing illness Pain Redness Fatigue Fever Anxiety Dry mouth Thirst Dark urine Bitter taste Red eyes Insomnia Fatigue Loose stools Poor appetite Dizziness Pale face Weak voice Reluctance to speak Sweating with little or no exertion Palpitations Insomnia Dry skin Dry hair Poor memory Paleness Scanty periods T: Red or Pale or Pale, thin and dry C: Thin and white or White or Yellow and greasy or Thick, sticky, dry and yellow P: Weak or Thin and choppy or Wiry or Rolling and rapid or Wiry, overflowing and rapid
Treatment Principle	Clear Heat Resolve toxicity Tonify Qi Nourish the Blood
Herb Formulas	Acute Leukemia #2
Points